wxGlade has been tested and run on Microsoft Windows, Linux, OS X.
Because wxGlade is written in Python using wxPython, it can also be run on any platform that supports Python and wxPython.
Especially the wxGlade requirements are:
Python 2 - at least 2.4 or any later version of Python 2
wxPython 2.8 or 3.0
Sometimes the wxPython module “wxversion” is packaged separately e.g. in Debian. Please install the “wxversion” package manually in such case,
wxWidgets 2.8 or 3.0, the wxWidgets are often bundled with wxPython
wxWidgets is available at http://www.wxwidgets.org and wxPython at http://www.wxpython.org.